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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX3X
All Species:
14.55
Human Site:
Y576
Identified Species:
22.86
UniProt:
O00571
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00571
NP_001347.3
662
73243
Y576
S
W
L
E
N
M
A
Y
E
H
H
Y
K
G
S
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
Y574
S
W
L
E
N
M
A
Y
E
H
Q
Y
K
G
G
Rhesus Macaque
Macaca mulatta
XP_001095294
910
100218
A825
P
S
W
L
E
N
M
A
Y
E
H
H
Y
K
G
Dog
Lupus familis
XP_861268
662
73195
Y576
S
W
L
E
N
M
A
Y
E
H
H
Y
K
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62167
662
73083
F576
S
W
L
E
N
M
A
F
E
H
H
Y
K
G
S
Rat
Rattus norvegicus
NP_001102328
659
72976
A573
P
S
W
L
E
N
M
A
F
E
H
H
Y
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512924
651
71975
Y562
S
W
L
E
N
M
A
Y
E
H
H
Y
K
G
S
Chicken
Gallus gallus
NP_001025971
651
72031
N565
E
V
P
S
W
L
E
N
M
A
Y
E
Q
H
H
Frog
Xenopus laevis
P24346
697
77284
W611
A
K
Q
E
V
P
S
W
L
E
N
M
A
Y
E
Zebra Danio
Brachydanio rerio
NP_571016
688
75828
W602
A
K
Q
E
V
P
S
W
L
E
S
L
A
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHP0
798
85063
D695
F
M
E
D
M
S
S
D
R
G
H
G
G
A
K
Honey Bee
Apis mellifera
XP_391829
701
78642
D616
E
L
P
P
W
L
D
D
M
F
S
E
A
R
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F9
646
69224
S540
D
W
L
T
R
Y
A
S
R
A
S
F
G
G
G
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
E532
G
L
M
E
I
L
N
E
A
N
Q
E
V
P
T
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
R588
A
F
L
E
T
I
A
R
E
S
S
F
G
G
G
Conservation
Percent
Protein Identity:
100
91.3
70.1
99.8
N.A.
98.6
95.3
N.A.
95.9
91.2
82.2
76.3
N.A.
51.7
58
N.A.
N.A.
Protein Similarity:
100
95.3
70.3
99.8
N.A.
99
97.1
N.A.
97.2
94.7
88
83.8
N.A.
63.4
70
N.A.
N.A.
P-Site Identity:
100
86.6
6.6
100
N.A.
93.3
6.6
N.A.
100
0
6.6
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
86.6
13.3
100
N.A.
100
13.3
N.A.
100
20
33.3
26.6
N.A.
20
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.5
49.4
52
Protein Similarity:
N.A.
N.A.
N.A.
64.6
65.2
64.8
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
47
14
7
14
0
0
20
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
0
7
14
0
0
0
0
0
0
0
% D
% Glu:
14
0
7
60
14
0
7
7
40
27
0
20
0
0
14
% E
% Phe:
7
7
0
0
0
0
0
7
7
7
0
14
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
7
0
7
20
47
34
% G
% His:
0
0
0
0
0
0
0
0
0
34
47
14
0
7
7
% H
% Ile:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
14
0
0
0
0
0
0
0
0
0
0
34
14
7
% K
% Leu:
0
14
47
14
0
20
0
0
14
0
0
7
0
0
0
% L
% Met:
0
7
7
0
7
34
14
0
14
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
34
14
7
7
0
7
7
0
0
0
0
% N
% Pro:
14
0
14
7
0
14
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
14
0
0
0
0
0
0
0
14
0
7
0
0
% Q
% Arg:
0
0
0
0
7
0
0
7
14
0
0
0
0
7
0
% R
% Ser:
34
14
0
7
0
7
20
7
0
7
27
0
0
0
27
% S
% Thr:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
7
0
0
14
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
40
14
0
14
0
0
14
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
27
7
0
7
34
14
14
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _